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Synthesis and biological evaluation of novel (123)I-labeled 4-(4-iodophenyl)butanoyl-L-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo.
Kallinen, Annukka; Todorov, Boyan; Kallionpää, Roope; Bäck, Susanne; Sarparanta, Mirkka; Raki, Mari; García-Horsman, Juan A; Bergström, Kim A; Wallén, Erik A A; Männistö, Pekka T; Airaksinen, Anu J.
Afiliação
  • Kallinen A; Laboratory of Radiochemistry, Department of Chemistry, P.O. Box 55, FI-00014 University of Helsinki, Finland. Electronic address: annukka.kallinen@helsinki.fi.
  • Todorov B; Laboratory of Radiochemistry, Department of Chemistry, P.O. Box 55, FI-00014 University of Helsinki, Finland.
  • Kallionpää R; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland.
  • Bäck S; Division of Pharmacology and Toxicology, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland.
  • Sarparanta M; Laboratory of Radiochemistry, Department of Chemistry, P.O. Box 55, FI-00014 University of Helsinki, Finland.
  • Raki M; Centre for Drug Research, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland.
  • García-Horsman JA; Division of Pharmacology and Toxicology, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland.
  • Bergström KA; Centre for Drug Research, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland; HUS Medical Imaging Center, Helsinki University Central Hospital, Finland.
  • Wallén EA; Division of Pharmaceutical Chemistry, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland.
  • Männistö PT; Division of Pharmacology and Toxicology, Faculty of Pharmacy, P.O. Box 56, 00014 University of Helsinki, Finland.
  • Airaksinen AJ; Laboratory of Radiochemistry, Department of Chemistry, P.O. Box 55, FI-00014 University of Helsinki, Finland. Electronic address: anu.airaksinen@helsinki.fi.
Eur J Med Chem ; 79: 436-45, 2014 May 22.
Article em En | MEDLINE | ID: mdl-24763264
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinas / Serina Endopeptidases / Nitrilas Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirrolidinas / Serina Endopeptidases / Nitrilas Limite: Animals Idioma: En Revista: Eur J Med Chem Ano de publicação: 2014 Tipo de documento: Article