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Btk inhibition suppresses agonist-induced human macrophage activation and inflammatory gene expression in RA synovial tissue explants.
Hartkamp, Linda M; Fine, Jay S; van Es, Inge E; Tang, Man Wai; Smith, Michael; Woods, John; Narula, Satwant; DeMartino, Julie; Tak, Paul P; Reedquist, Kris A.
Afiliação
  • Hartkamp LM; Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Fine JS; Department of Inflammation Discovery, Hoffmann-La Roche, Inc., Nutley, New Jersey, USA.
  • van Es IE; Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Tang MW; Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
  • Smith M; Department of Inflammation Discovery, Hoffmann-La Roche, Inc., Nutley, New Jersey, USA.
  • Woods J; Department of Inflammation Discovery, Hoffmann-La Roche, Inc., Nutley, New Jersey, USA.
  • Narula S; Department of Inflammation Discovery, Hoffmann-La Roche, Inc., Nutley, New Jersey, USA.
  • DeMartino J; Department of Inflammation Discovery, Hoffmann-La Roche, Inc., Nutley, New Jersey, USA.
  • Tak PP; Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands GlaxoSmithKline, Stevenage, and University of Cambridge, Cambridge, UK.
  • Reedquist KA; Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Department of Clinical Immunology and Rheumatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Ann Rheum Dis ; 74(8): 1603-11, 2015 Aug.
Article em En | MEDLINE | ID: mdl-24764451
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Membrana Sinovial / Proteínas Tirosina Quinases / Isoquinolinas Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Membrana Sinovial / Proteínas Tirosina Quinases / Isoquinolinas Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Holanda