Heterogeneity of tempo and mode of mitochondrial DNA evolution among mammalian orders.
Jpn J Genet
; 64(4): 243-58, 1989 Aug.
Article
em En
| MEDLINE
| ID: mdl-2483667
ABSTRACT
A statistical analysis of complete DNA sequence data of mitochondrial genomes from human, bovine, and mouse (and partial sequence of rat) indicates that the transversion rate is lower in bovine than in human and murids, and that it is probably lower in human than in murids. However, it is unknown whether the transition rate is also lower in bovine. It is shown that the L-strand of human mitochondrial DNA has significantly higher C content and lower T and A contents than those of bovine and murids. This suggests that a directional mutation pressure which tends to change base composition has been operating in the human lineage.
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Base de dados:
MEDLINE
Assunto principal:
DNA Mitocondrial
/
Evolução Biológica
Tipo de estudo:
Health_economic_evaluation
/
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Jpn J Genet
Assunto da revista:
BIOTECNOLOGIA
/
GENETICA
Ano de publicação:
1989
Tipo de documento:
Article