Your browser doesn't support javascript.
loading
Cooperative activation with chiral nucleophilic catalysts and N-haloimides: enantioselective iodolactonization of 4-arylmethyl-4-pentenoic acids.
Nakatsuji, Hidefumi; Sawamura, Yasuhiro; Sakakura, Akira; Ishihara, Kazuaki.
Afiliação
  • Nakatsuji H; Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8603 (Japan) http://www.ishihara-lab.net.
Angew Chem Int Ed Engl ; 53(27): 6974-7, 2014 Jul 01.
Article em En | MEDLINE | ID: mdl-24840957
Chiral triaryl phosphates promote the enantioselective iodolactonization of 4-substituted 4-pentenoic acids to give the corresponding iodolactones in high yields with high enantioselectivity. N-Chlorophthalimide (NCP) is employed as a Lewis acidic activator and oxidant of I2 for the present iodolactonization. In combination with 1.5 equivalents of NCP, only 0.5 equivalents of I2 are sufficient to generate the iodinating reagent.
Assuntos
Palavras-chave

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Graxos Monoinsaturados / Imidas / Lactonas Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácidos Graxos Monoinsaturados / Imidas / Lactonas Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2014 Tipo de documento: Article