Measurement of serum transferrin by the gamma-gamma perturbed angular correlation method. Differences between normal and cancer serum.
Biol Trace Elem Res
; 22(1): 1-7, 1989 Oct.
Article
em En
| MEDLINE
| ID: mdl-2484222
ABSTRACT
In this work, the average perturbed angular correlation integral attenuation factor G2 of the transferrin in the serums from the normals and the patients with liver cancer were determined using time integral perturbed angular correlation method (PAC). The average values of G2 were 0.1945 +/- 0.0155 for the cancer serum transferrin and 0.2865 +/- 0.0411 for the normal serum transferrin. The difference between these two groups is significant. Mathematical deduction and theoretical analysis suggested that the equivalent radius of the transferrin molecules in the serum of cancer patients becomes smaller than normal, because of a change in the molecular conformation. Similar results were also observed in experiments with rat serum transferrin.
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Base de dados:
MEDLINE
Assunto principal:
Transferrina
/
Neoplasias Hepáticas
Limite:
Humans
Idioma:
En
Revista:
Biol Trace Elem Res
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
China