Expanded Utility of the ß-Glucuronide Linker: ADCs That Deliver Phenolic Cytotoxic Agents.

Jeffrey, Scott C; De Brabander, Jef; Miyamoto, Jamie; Senter, Peter D

Jeffrey, Scott C; De Brabander, Jef; Miyamoto, Jamie; Senter, Peter D.

Afiliação

Jeffrey SC; Seattle Genetics, 21823 30th Drive SE, Bothell, Washington 98021.
De Brabander J; Department of Biochemistry and Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9038.
Miyamoto J; Seattle Genetics, 21823 30th Drive SE, Bothell, Washington 98021.
Senter PD; Seattle Genetics, 21823 30th Drive SE, Bothell, Washington 98021.

ACS Med Chem Lett ; 1(6): 277-80, 2010 Sep 09.

Article em En | MEDLINE | ID: mdl-24900208

Palavras-chave

CD30-positive L540cy cell line; CD70-positive Caki-1 cell line; N,N'-dimethylethylene diamine; antibody−drug conjugates; phenolic cytotoxic agents; ß-Glucuronide linker

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2010 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2010 Tipo de documento: Article