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Identification of NAE Inhibitors Exhibiting Potent Activity in Leukemia Cells: Exploring the Structural Determinants of NAE Specificity.
Lukkarila, Julie L; da Silva, Sara R; Ali, Mohsin; Shahani, Vijay M; Xu, G Wei; Berman, Judd; Roughton, Andrew; Dhe-Paganon, Sirano; Schimmer, Aaron D; Gunning, Patrick T.
Afiliação
  • Lukkarila JL; Department of Chemistry, University of Toronto Mississauga , 3359 Mississauga Road North, Mississauga, ON, L5L1C6, Canada.
  • da Silva SR; Department of Chemistry, University of Toronto Mississauga , 3359 Mississauga Road North, Mississauga, ON, L5L1C6, Canada.
  • Ali M; Division of Hematology and Oncology, The Princess Margaret Hospital and the Ontario Cancer Institute , 610 University Avenue, Toronto, ON, M5G2M9, Canada.
  • Shahani VM; Department of Chemistry, University of Toronto Mississauga , 3359 Mississauga Road North, Mississauga, ON, L5L1C6, Canada.
  • Xu GW; Division of Hematology and Oncology, The Princess Margaret Hospital and the Ontario Cancer Institute , 610 University Avenue, Toronto, ON, M5G2M9, Canada.
  • Berman J; Dalton Medicinal Chemistry Inc. , 349 Wildcat Road, Toronto, ON, M3J 2S3, Canada.
  • Roughton A; Dalton Medicinal Chemistry Inc. , 349 Wildcat Road, Toronto, ON, M3J 2S3, Canada.
  • Dhe-Paganon S; Structural Genomics Consortium, University of Toronto , 100 College Street, Toronto, ON, M5G1L5, Canada.
  • Schimmer AD; Division of Hematology and Oncology, The Princess Margaret Hospital and the Ontario Cancer Institute , 610 University Avenue, Toronto, ON, M5G2M9, Canada.
  • Gunning PT; Department of Chemistry, University of Toronto Mississauga , 3359 Mississauga Road North, Mississauga, ON, L5L1C6, Canada.
ACS Med Chem Lett ; 2(8): 577-82, 2011 Aug 11.
Article em En | MEDLINE | ID: mdl-24900352
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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2011 Tipo de documento: Article País de afiliação: Canadá