Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation.

Deplus, Rachel; Denis, Hélène; Putmans, Pascale; Calonne, Emilie; Fourrez, Marie; Yamamoto, Kazuhiko; Suzuki, Akari; Fuks, François

Deplus, Rachel; Denis, Hélène; Putmans, Pascale; Calonne, Emilie; Fourrez, Marie; Yamamoto, Kazuhiko; Suzuki, Akari; Fuks, François.

Afiliação

Deplus R; Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium ffuks@ulb.ac.be.
Denis H; Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.
Putmans P; Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.
Calonne E; Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.
Fourrez M; Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium.
Yamamoto K; Laboratory for Autoimmune diseases, Center for Integrative Medical Science, The Institute of Physical and Chemical Research (RIKEN), 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa, Japan.
Suzuki A; Laboratory for Autoimmune diseases, Center for Integrative Medical Science, The Institute of Physical and Chemical Research (RIKEN), 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa, Japan.
Fuks F; Laboratory of Cancer Epigenetics, Faculty of Medicine, Université Libre de Bruxelles, 808 route de Lennik, 1070 Brussels, Belgium ffuks@ulb.ac.be.

Nucleic Acids Res ; 42(13): 8285-96, 2014 Jul.

Article em En | MEDLINE | ID: mdl-24957603

Assuntos

Citrulina/metabolismo; DNA (Citosina-5-)-Metiltransferases/metabolismo; Metilação de DNA; Hidrolases/metabolismo; Animais; Linhagem Celular; DNA Metiltransferase 3A; Estabilidade Enzimática; Humanos; Camundongos; Camundongos Knockout; Estrutura Terciária de Proteína; Proteína-Arginina Desiminase do Tipo 4; Desiminases de Arginina em Proteínas

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Citrulina / Metilação de DNA / DNA (Citosina-5-)-Metiltransferases / Hidrolases Limite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Bélgica

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