Taming the carboxyl group for directed carbometalation: observations on the use of anions, dianions and ester enolates.

Desrat, Sandy; Gray, Philip J; Penny, Matthew R; Motherwell, William B

Desrat, Sandy; Gray, Philip J; Penny, Matthew R; Motherwell, William B.

Afiliação

Desrat S; Department of Chemistry, University College London, 20 Gordon Street, London WC1H 0AJ (United Kingdom), Tel: +(44) 2076797524.

Chemistry ; 20(29): 8918-22, 2014 Jul 14.

Article em En | MEDLINE | ID: mdl-24961599

ABSTRACT

ABSTRACT

Carboxylate anions, dianions and ester enolates provide simultaneous protection and activation for directed carbometalation reactions. Advantage can be taken of the bis-carbanionic character of the intermediate for further controlled C-C bond forming reactions.

Palavras-chave

Grignard reagent; allene; carbometalation; copper; enolate

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2014 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Chemistry Assunto da revista: QUIMICA Ano de publicação: 2014 Tipo de documento: Article