Crystal structure reveals conservation of amyloid-ß conformation recognized by 3D6 following humanization to bapineuzumab.

Feinberg, Hadar; Saldanha, José W; Diep, Linnea; Goel, Amita; Widom, Angela; Veldman, Geertruida M; Weis, William I; Schenk, Dale; Basi, Guriqbal S

Feinberg, Hadar; Saldanha, José W; Diep, Linnea; Goel, Amita; Widom, Angela; Veldman, Geertruida M; Weis, William I; Schenk, Dale; Basi, Guriqbal S.

Afiliação

Feinberg H; Departments of Structural Biology and of Molecular & Cellular Physiology, 299 Campus Drive, Stanford University School of Medicine, Stanford, CA 94305, USA.
Saldanha JW; National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.
Diep L; Elan Pharmaceuticals, Inc. 300 Technology Sq., Cambridge, MA 02139, USA.
Goel A; Elan Pharmaceuticals, Inc. 300 Technology Sq., Cambridge, MA 02139, USA.
Widom A; Pfizer, Cambridge, MA, USA.
Veldman GM; Abbvie Bioresearch Center, Worcester, MA, USA.
Weis WI; Departments of Structural Biology and of Molecular & Cellular Physiology, 299 Campus Drive, Stanford University School of Medicine, Stanford, CA 94305, USA.
Schenk D; Prothena Biosciences, Inc., 650 Gateway Blvd., San Francisco, CA 94080, USA.
Basi GS; Elan Pharmaceuticals, Inc. 300 Technology Sq., Cambridge, MA 02139, USA.

Alzheimers Res Ther ; 6(3): 31, 2014.

Article em En | MEDLINE | ID: mdl-25024748

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Alzheimers Res Ther Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos

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