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Physicochemical property-driven optimization of diarylaniline compounds as potent HIV-1 non-nucleoside reverse transcriptase inhibitors.
Liu, Na; Qin, Bingjie; Sun, Lian-Qi; Yu, Fei; Lu, Lu; Jiang, Shibo; Lee, Kuo-Hsiung; Xie, Lan.
Afiliação
  • Liu N; Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
  • Qin B; Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
  • Sun LQ; Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China.
  • Yu F; Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Medical College and Institute of Medical Microbiology, Fudan University, Shanghai 200032, China; Lindsley F. Kimball Research Institute, New York Blood Center, NY 10065, USA.
  • Lu L; Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Medical College and Institute of Medical Microbiology, Fudan University, Shanghai 200032, China.
  • Jiang S; Key Laboratory of Medical Molecular Virology of Ministries of Education and Health, Shanghai Medical College and Institute of Medical Microbiology, Fudan University, Shanghai 200032, China; Lindsley F. Kimball Research Institute, New York Blood Center, NY 10065, USA.
  • Lee KH; Natural Products Research Laboratories, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599-7568, USA; Chinese Medicine Research and Development Center, China Medical University and Hospital, Taichung, Taiwan. Electronic address: khlee@unc.edu.
  • Xie L; Beijing Institute of Pharmacology & Toxicology, 27 Tai-Ping Road, Beijing 100850, China. Electronic address: lanxie4@gmail.com.
Bioorg Med Chem Lett ; 24(16): 3719-23, 2014 Aug 15.
Article em En | MEDLINE | ID: mdl-25042339

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / Transcriptase Reversa do HIV / Compostos de Anilina Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Inibidores da Transcriptase Reversa / Fármacos Anti-HIV / Transcriptase Reversa do HIV / Compostos de Anilina Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: China