Development and characterization of hydrogels based on natural polysaccharides: policaju and chitosan.
Mater Sci Eng C Mater Biol Appl
; 42: 219-26, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-25063113
ABSTRACT
The development of hydrogels based on natural polysaccharides was investigated by preparing mixtures of policaju/chitosan at weight ratios of 14 and 23. Utilizing dynamic light scattering (DLS) techniques for these mixtures, an increase on the hydrodynamic particle radius was observed varying their pH from 3.0 to 12.0. Furthermore, a reduction of ζ-potential was also observed for the same pH interval. Following rounds of drying/hydration cycles at a specific pH value, hydrogel matrices were formed. The pore size distribution of these formed hydrogels was examined using scanning electron microscopy. Further FT-IR analyses confirmed a physical interaction between the polysaccharides policaju and chitosan. Swelling experiments revealed water uptake values, after 24h of immersion in water, close to 270% for 14, and 320% for 23 hydrogels. Finally, rheological measurements were then conducted in order to confirm hydrogel viscoelastic features. These results indicate a promising road to biomaterials fabrication and biomedical applications.
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En
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Mater Sci Eng C Mater Biol Appl
Ano de publicação:
2014
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Article