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Tautomerism provides a molecular explanation for the mutagenic properties of the anti-HIV nucleoside 5-aza-5,6-dihydro-2'-deoxycytidine.
Li, Deyu; Fedeles, Bogdan I; Singh, Vipender; Peng, Chunte Sam; Silvestre, Katherine J; Simi, Allison K; Simpson, Jeffrey H; Tokmakoff, Andrei; Essigmann, John M.
Afiliação
  • Li D; Departments of Chemistry andBiological Engineering, andCenter for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Fedeles BI; Departments of Chemistry andBiological Engineering, andCenter for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Singh V; Departments of Chemistry andBiological Engineering, andCenter for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139.
  • Peng CS; Departments of Chemistry and.
  • Silvestre KJ; Departments of Chemistry and.
  • Simi AK; Biological Engineering, and.
  • Simpson JH; Departments of Chemistry and.
  • Tokmakoff A; Departments of Chemistry and jessig@mit.edu tokmakoff@uchicago.edu.
  • Essigmann JM; Departments of Chemistry andBiological Engineering, andCenter for Environmental Health Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139 jessig@mit.edu tokmakoff@uchicago.edu.
Proc Natl Acad Sci U S A ; 111(32): E3252-9, 2014 Aug 12.
Article em En | MEDLINE | ID: mdl-25071207

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azacitidina / HIV / Fármacos Anti-HIV / Desoxicitidina / Mutagênicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Azacitidina / HIV / Fármacos Anti-HIV / Desoxicitidina / Mutagênicos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article