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The PARP inhibitor Olaparib disrupts base excision repair of 5-aza-2'-deoxycytidine lesions.
Orta, Manuel Luis; Höglund, Andreas; Calderón-Montaño, José Manuel; Domínguez, Inmaculada; Burgos-Morón, Estefanía; Visnes, Torkild; Pastor, Nuria; Ström, Cecilia; López-lázaro, Miguel; Helleday, Thomas.
Afiliação
  • Orta ML; Department of Cell Biology, Faculty of Biology, University of Seville, Avda. Reina Mercedes 6, 41012 Seville, Spain Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Swede
  • Höglund A; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden.
  • Calderón-Montaño JM; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden Department of Pharmacology, Faculty of Pharmacy, University of Seville, c/Professor García González, No. 2, 41012
  • Domínguez I; Department of Cell Biology, Faculty of Biology, University of Seville, Avda. Reina Mercedes 6, 41012 Seville, Spain.
  • Burgos-Morón E; Department of Pharmacology, Faculty of Pharmacy, University of Seville, c/Professor García González, No. 2, 41012 Seville, Spain.
  • Visnes T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden.
  • Pastor N; Department of Cell Biology, Faculty of Biology, University of Seville, Avda. Reina Mercedes 6, 41012 Seville, Spain.
  • Ström C; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden.
  • López-lázaro M; Department of Pharmacology, Faculty of Pharmacy, University of Seville, c/Professor García González, No. 2, 41012 Seville, Spain.
  • Helleday T; Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, S-171 21 Stockholm, Sweden thomas.helleday@scilifelab.se.
Nucleic Acids Res ; 42(14): 9108-20, 2014 Aug.
Article em En | MEDLINE | ID: mdl-25074383
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Azacitidina / Reparo do DNA / Inibidores Enzimáticos / Inibidores de Poli(ADP-Ribose) Polimerases / Antimetabólitos Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Azacitidina / Reparo do DNA / Inibidores Enzimáticos / Inibidores de Poli(ADP-Ribose) Polimerases / Antimetabólitos Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2014 Tipo de documento: Article