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Discovery and pharmacological profile of new hydrophilic 5-HT(4) receptor antagonists.
Brudeli, Bjarne; Navaratnarajah, Mirusha; Andressen, Kjetil Wessel; Manfra, Ornella; Moltzau, Lise Román; Nilsen, Nils Olav; Levy, Finn Olav; Klaveness, Jo.
Afiliação
  • Brudeli B; Drug Discovery Laboratory AS, Oslo Innovation Center, N-0349 Oslo, Norway; Department of Medicinal Chemistry, School of Pharmacy, University of Oslo, PO Box 1068 Blindern, N-0316 Oslo, Norway.
  • Navaratnarajah M; Department of Pharmacology, Faculty of Medicine, University of Oslo and Oslo University Hospital, PO Box 1057 Blindern, N-0316 Oslo, Norway; Department of Medicinal Chemistry, School of Pharmacy, University of Oslo, PO Box 1068 Blindern, N-0316 Oslo, Norway.
  • Andressen KW; Department of Pharmacology, Faculty of Medicine, University of Oslo and Oslo University Hospital, PO Box 1057 Blindern, N-0316 Oslo, Norway; K.G. Jebsen Cardiac Research Centre and Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Norway.
  • Manfra O; Department of Pharmacology, Faculty of Medicine, University of Oslo and Oslo University Hospital, PO Box 1057 Blindern, N-0316 Oslo, Norway; K.G. Jebsen Cardiac Research Centre and Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Norway.
  • Moltzau LR; Department of Pharmacology, Faculty of Medicine, University of Oslo and Oslo University Hospital, PO Box 1057 Blindern, N-0316 Oslo, Norway; K.G. Jebsen Cardiac Research Centre and Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Norway.
  • Nilsen NO; Drug Discovery Laboratory AS, Oslo Innovation Center, N-0349 Oslo, Norway.
  • Levy FO; Department of Pharmacology, Faculty of Medicine, University of Oslo and Oslo University Hospital, PO Box 1057 Blindern, N-0316 Oslo, Norway; K.G. Jebsen Cardiac Research Centre and Center for Heart Failure Research, Faculty of Medicine, University of Oslo, Norway.
  • Klaveness J; Department of Medicinal Chemistry, School of Pharmacy, University of Oslo, PO Box 1068 Blindern, N-0316 Oslo, Norway. Electronic address: jo.klaveness@farmasi.uio.no.
Bioorg Med Chem Lett ; 24(18): 4598-4602, 2014 Sep 15.
Article em En | MEDLINE | ID: mdl-25149506
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propilenoglicóis / Receptores 5-HT4 de Serotonina / Descoberta de Drogas / Antagonistas do Receptor 5-HT4 de Serotonina Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Noruega
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Propilenoglicóis / Receptores 5-HT4 de Serotonina / Descoberta de Drogas / Antagonistas do Receptor 5-HT4 de Serotonina Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Noruega