Comparison of topical and intravenous tranexamic acid on blood loss and transfusion rates in total hip arthroplasty.
J Arthroplasty
; 29(11): 2113-6, 2014 Nov.
Article
em En
| MEDLINE
| ID: mdl-25155138
ABSTRACT
The objective of this study was to determine whether topical tranexamic acid (TXA) carried similar hemostatic effect compared with intravenous TXA in total hip arthroplasty (THA). Three hundred and three THA patients were enrolled and randomized into 3 groups no TXA group, topical and intravenous TXA group. The results showed that the topical and intravenous TXA group had reduced but similar blood transfusion rates (5.88% v. s. 5.94%, P = 0.816). No significant difference was detected in total blood loss between the two TXA groups [(963.4 ± 421.3) ml vs. (958.5 ± 422) ml P = 0.733]. We conclude that topical use of TXA was equally effective and safe compared with intravenous TXA in reducing blood loss and transfusion rate following THA without substantial complications.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ácido Tranexâmico
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Artroplastia de Quadril
/
Antifibrinolíticos
Tipo de estudo:
Clinical_trials
Limite:
Aged
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
En
Revista:
J Arthroplasty
Assunto da revista:
ORTOPEDIA
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
China