Sleep and respiratory physiology in adults.
Clin Chest Med
; 35(3): 469-81, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-25156763
ABSTRACT
Respiration during sleep is determined by metabolic demand; respiratory drive is determined by a central respiratory generator. Changes in pharyngeal dilator muscle tone resulting in increased upper airway resistance and collapsibility contribute to hypoventilation. Relative hypotonia of respiratory muscles, body posture changes, and altered ventilatory control result in additional physiologic changes contributing to hypoventilation. This article reviews mechanisms of central control of respiration and normal upper and lower airway physiology. Understanding sleep-related changes in respiratory physiology will help in developing new therapies to prevent hypoventilation in susceptible populations.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fenômenos Fisiológicos Respiratórios
/
Sono
Limite:
Humans
Idioma:
En
Revista:
Clin Chest Med
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Estados Unidos