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Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial.
San-Miguel, Jesús F; Hungria, Vânia T M; Yoon, Sung-Soo; Beksac, Meral; Dimopoulos, Meletios Athanasios; Elghandour, Ashraf; Jedrzejczak, Wieslaw Wiktor; Günther, Andreas; Nakorn, Thanyaphong Na; Siritanaratkul, Noppadol; Corradini, Paolo; Chuncharunee, Suporn; Lee, Je-Jung; Schlossman, Robert L; Shelekhova, Tatiana; Yong, Kwee; Tan, Daryl; Numbenjapon, Tontanai; Cavenagh, Jamie D; Hou, Jian; LeBlanc, Richard; Nahi, Hareth; Qiu, Lugui; Salwender, Hans; Pulini, Stefano; Moreau, Philippe; Warzocha, Krzysztof; White, Darrell; Bladé, Joan; Chen, WenMing; de la Rubia, Javier; Gimsing, Peter; Lonial, Sagar; Kaufman, Jonathan L; Ocio, Enrique M; Veskovski, Ljupco; Sohn, Sang Kyun; Wang, Ming-Chung; Lee, Jae Hoon; Einsele, Hermann; Sopala, Monika; Corrado, Claudia; Bengoudifa, Bourras-Rezki; Binlich, Florence; Richardson, Paul G.
Afiliação
  • San-Miguel JF; Clínica Universidad de Navarra-CIMA, Pamplona, Spain. Electronic address: sanmiguel@unav.es.
  • Hungria VT; Santa Casa de Misericordia de São Paulo Hospital, São Paulo, Brazil.
  • Yoon SS; Seoul National University Hospital, Seoul, South Korea.
  • Beksac M; Ankara University School of Medicine, Ankara, Turkey.
  • Dimopoulos MA; University of Athens School of Medicine, Athens, Greece.
  • Elghandour A; Alexandria University, Alexandria, Egypt.
  • Jedrzejczak WW; Medical University of Warsaw, Warsaw, Poland.
  • Günther A; University of Kiel, Kiel, Germany.
  • Nakorn TN; Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
  • Siritanaratkul N; Siriraj Hospital, Bangkok, Thailand.
  • Corradini P; Fondazione IRCCS Istituto Nazionale dei Tumori, University of Milan, Milan, Italy.
  • Chuncharunee S; Ramathibodi Hospital, Bangkok, Thailand.
  • Lee JJ; Chonnam National University Hwasun Hospital, Hwasun, South Korea.
  • Schlossman RL; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Shelekhova T; Clinic of Professional Pathology and Haematology, Saratov State Medical University, Saratov, Russia.
  • Yong K; UCL Cancer Institute, University College London, London, UK.
  • Tan D; Singapore General Hospital, Singapore.
  • Numbenjapon T; Phramongkutklao Hospital, Bangkok, Thailand.
  • Cavenagh JD; St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.
  • Hou J; Chang Zheng Hospital, Shanghai, China.
  • LeBlanc R; Maisonneuve-Rosemont Hospital and University of Montreal, Montreal, QC, Canada.
  • Nahi H; Karolinska University Hospital, Stockholm, Sweden.
  • Qiu L; State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China.
  • Salwender H; Asklepios Clinic Altona, Hamburg, Germany.
  • Pulini S; Spirito Santo Hospital, Pescara, Italy.
  • Moreau P; Nantes University Hospital, Nantes, France.
  • Warzocha K; Institute of Haematology and Transfusion Medicine, Warsaw, Poland.
  • White D; Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada.
  • Bladé J; Hospital Clínic de Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain.
  • Chen W; Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
  • de la Rubia J; University Hospital La Fe and Universidad Católica San Vicente Mártir, Valencia, Spain.
  • Gimsing P; Rigshospitalet and University of Copenhagen, Copenhagen, Denmark.
  • Lonial S; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
  • Kaufman JL; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, USA.
  • Ocio EM; University Hospital and Cancer Research Center, University of Salamanca-Instituto de Investigación Biomédica de Salamanca, Instituto de Biología Molecular y Celular del Cáncer, Salamanca, Spain.
  • Veskovski L; Sahlgrenska University Hospital, Göteborg, Sweden.
  • Sohn SK; Kyungpook National University, Daegu, South Korea.
  • Wang MC; Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
  • Lee JH; Gachon University Gil Medical Center, Incheon, South Korea.
  • Einsele H; University Hospital Würzburg, Würzburg, Germany.
  • Sopala M; Novartis Pharma AG, Basel, Switzerland.
  • Corrado C; Novartis Pharma AG, Basel, Switzerland.
  • Bengoudifa BR; Novartis Pharma AG, Basel, Switzerland.
  • Binlich F; Novartis Pharma SAS, Rueil-Malmaison, France.
  • Richardson PG; Dana-Farber Cancer Institute, Boston, MA, USA.
Lancet Oncol ; 15(11): 1195-206, 2014 Oct.
Article em En | MEDLINE | ID: mdl-25242045
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Mieloma Múltiplo / Recidiva Local de Neoplasia Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Protocolos de Quimioterapia Combinada Antineoplásica / Mieloma Múltiplo / Recidiva Local de Neoplasia Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Oncol Assunto da revista: NEOPLASIAS Ano de publicação: 2014 Tipo de documento: Article