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Mechanism-based inactivation of human cytochrome P450 3A4 by two piperazine-containing compounds.
Bolles, Amanda K; Fujiwara, Rina; Briggs, Erran D; Nomeir, Amin A; Furge, Laura Lowe.
Afiliação
  • Bolles AK; Amin Nomeir Pharmaceutical Consulting, LLC, Milford, New Jersey (A.A.N.); and Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan (A.K.B., R.F., E.D.B., L.L.F.).
  • Fujiwara R; Amin Nomeir Pharmaceutical Consulting, LLC, Milford, New Jersey (A.A.N.); and Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan (A.K.B., R.F., E.D.B., L.L.F.).
  • Briggs ED; Amin Nomeir Pharmaceutical Consulting, LLC, Milford, New Jersey (A.A.N.); and Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan (A.K.B., R.F., E.D.B., L.L.F.).
  • Nomeir AA; Amin Nomeir Pharmaceutical Consulting, LLC, Milford, New Jersey (A.A.N.); and Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan (A.K.B., R.F., E.D.B., L.L.F.).
  • Furge LL; Amin Nomeir Pharmaceutical Consulting, LLC, Milford, New Jersey (A.A.N.); and Department of Chemistry, Kalamazoo College, Kalamazoo, Michigan (A.K.B., R.F., E.D.B., L.L.F.) laura.furge@kzoo.edu.
Drug Metab Dispos ; 42(12): 2087-96, 2014 Dec.
Article em En | MEDLINE | ID: mdl-25273356
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Citocromo P-450 CYP3A / Inibidores das Enzimas do Citocromo P-450 Limite: Humans Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Citocromo P-450 CYP3A / Inibidores das Enzimas do Citocromo P-450 Limite: Humans Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2014 Tipo de documento: Article