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Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions.
Lin, Yun; Damjanovic, Amanda; Metter, E Jeffrey; Nguyen, Huy; Truong, Thai; Najarro, Kevin; Morris, Christa; Longo, Dan L; Zhan, Ming; Ferrucci, Luigi; Hodes, Richard J; Weng, Nan-ping.
Afiliação
  • Lin Y; *Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Damjanovic A; *Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Metter EJ; †Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224,U.S.A.
  • Nguyen H; *Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Truong T; *Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Najarro K; *Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Morris C; ‡Flow Cytometry Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Longo DL; §Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Zhan M; ║Bioinformatics Unit, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
  • Ferrucci L; †Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224,U.S.A.
  • Hodes RJ; ¶National Institute on Aging and Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, U.S.A.
  • Weng NP; *Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, U.S.A.
Clin Sci (Lond) ; 128(6): 367-77, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25317735
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Subpopulações de Linfócitos / Telomerase / Homeostase do Telômero Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / Subpopulações de Linfócitos / Telomerase / Homeostase do Telômero Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos