Matrix metalloproteinase-3 promotes early blood-spinal cord barrier disruption and hemorrhage and impairs long-term neurological recovery after spinal cord injury.

Lee, Jee Youn; Choi, Hae Young; Ahn, Hyun-Jong; Ju, Bong Gun; Yune, Tae Young

Lee, Jee Youn; Choi, Hae Young; Ahn, Hyun-Jong; Ju, Bong Gun; Yune, Tae Young.

Afiliação

Lee JY; Age-Related and Brain Diseases Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Neurodegeneration Control Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Choi HY; Age-Related and Brain Diseases Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Neurodegeneration Control Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Ahn HJ; Department of Microbiology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.
Ju BG; Department of Life Science, Sogang University, Seoul, Republic of Korea.
Yune TY; Age-Related and Brain Diseases Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Neurodegeneration Control Research Center, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; Department of Biochemistry and Molecular Biology, School of Medicine, Kyu

Am J Pathol ; 184(11): 2985-3000, 2014 Nov.

Article em En | MEDLINE | ID: mdl-25325922

Assuntos

Barreira Hematoencefálica/metabolismo; Hemorragia/metabolismo; Metaloproteinase 3 da Matriz/metabolismo; Recuperação de Função Fisiológica/fisiologia; Traumatismos da Medula Espinal/metabolismo; Medula Espinal/metabolismo; Animais; Permeabilidade Capilar; Modelos Animais de Doenças; Masculino; Metaloproteinase 3 da Matriz/genética; Camundongos; Camundongos Knockout; NF-kappa B/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medula Espinal / Traumatismos da Medula Espinal / Barreira Hematoencefálica / Metaloproteinase 3 da Matriz / Recuperação de Função Fisiológica / Hemorragia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2014 Tipo de documento: Article

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