Targeted therapy in sarcomas other than GIST tumors.
J Surg Oncol
; 111(5): 632-40, 2015 Apr.
Article
em En
| MEDLINE
| ID: mdl-25330750
ABSTRACT
Non-GIST soft tissue sarcomas are a heterogeneous grouping of mesenchymal tumors that comprise less than 1% of adult malignancies. Treatment continues to be based on cytotoxic chemotherapy regimens. However, characterization of the molecular pathway deregulations that drive these tumors has led to the emergence of more customized treatment options. In this review, we focus on the multitude of molecular inhibitors targeting angiogenesis and cell cycle pathways being tested in clinical trials.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Sarcoma
/
Antineoplásicos
Limite:
Humans
Idioma:
En
Revista:
J Surg Oncol
Ano de publicação:
2015
Tipo de documento:
Article