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Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation.
Lacek, Krzysztof; Urbanowicz, Richard A; Troise, Fulvia; De Lorenzo, Claudia; Severino, Valeria; Di Maro, Antimo; Tarr, Alexander W; Ferrara, Francesca; Ploss, Alexander; Temperton, Nigel; Ball, Jonathan K; Nicosia, Alfredo; Cortese, Riccardo; Pessi, Antonello.
Afiliação
  • Lacek K; From Ceinge Biotecnologie Avanzate S.C.R.L., Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy, the Laboratory of Virus Molecular Biology, University of Gdansk, 80-822 Gdansk, Poland.
  • Urbanowicz RA; the School of Life Sciences and Nottingham Digestive Diseases Centre Biomedical Research Unit, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
  • Troise F; From Ceinge Biotecnologie Avanzate S.C.R.L., Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy.
  • De Lorenzo C; From Ceinge Biotecnologie Avanzate S.C.R.L., Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy, the Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via Pansini 5, 80131 Napoli (NA), Italy.
  • Severino V; the Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, 81100 Caserta (CE), Italy.
  • Di Maro A; the Department of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, 81100 Caserta (CE), Italy.
  • Tarr AW; the School of Life Sciences and Nottingham Digestive Diseases Centre Biomedical Research Unit, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
  • Ferrara F; the Viral Pseudotype Unit, Infectious Diseases and Allergy group, School of Pharmacy, University of Kent, Kent ME4 4TB, United Kingdom.
  • Ploss A; the Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, and.
  • Temperton N; the Viral Pseudotype Unit, Infectious Diseases and Allergy group, School of Pharmacy, University of Kent, Kent ME4 4TB, United Kingdom.
  • Ball JK; the School of Life Sciences and Nottingham Digestive Diseases Centre Biomedical Research Unit, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, United Kingdom.
  • Nicosia A; From Ceinge Biotecnologie Avanzate S.C.R.L., Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy, the Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via Pansini 5, 80131 Napoli (NA), Italy.
  • Cortese R; From Ceinge Biotecnologie Avanzate S.C.R.L., Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy.
  • Pessi A; From Ceinge Biotecnologie Avanzate S.C.R.L., Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy, JV Bio, Via Gaetano Salvatore 486, 80145 Napoli (NA), Italy a.pessi@jvbio.com.
J Biol Chem ; 289(50): 35015-28, 2014 Dec 12.
Article em En | MEDLINE | ID: mdl-25342747

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Colesterol / HIV-1 / Anticorpos Neutralizantes / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Polônia

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Colesterol / HIV-1 / Anticorpos Neutralizantes / Anticorpos Monoclonais Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Polônia