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Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory response.
Quiniou, Christiane; Domínguez-Punaro, Maria; Cloutier, Frank; Erfani, Atefeh; Ennaciri, Jamila; Sivanesan, Durgajini; Sanchez, Mélanie; Chognard, Gaëlle; Hou, Xin; Rivera, José Carlos; Beauchamp, Claudine; Charron, Guy; Vilquin, Marie; Kuchroo, Vijay; Michnick, Stephen; Rioux, John D; Lesage, Sylvie; Chemtob, Sylvain.
Afiliação
  • Quiniou C; Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Centre, Montréal, Canada;
  • Domínguez-Punaro M; Maisonneuve-Rosemont Hospital, Research Center, Montreal, Canada;
  • Cloutier F; Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Centre, Montréal, Canada;
  • Erfani A; Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Centre, Montréal, Canada;
  • Ennaciri J; Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Centre, Montréal, Canada;
  • Sivanesan D; Department of Pharmacology and Therapeutics, McGill University, Montréal, Canada;
  • Sanchez M; Department of Biochemistry, Université de Montréal, Montréal, Canada;
  • Chognard G; Maisonneuve-Rosemont Hospital, Research Center, Montreal, Canada; Department of Microbiology and Immunology, Université de Montréal, Montréal, Canada;
  • Hou X; Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Centre, Montréal, Canada;
  • Rivera JC; Maisonneuve-Rosemont Hospital, Research Center, Montreal, Canada;
  • Beauchamp C; Montreal Heart Institute, Montréal, Canada;
  • Charron G; Montreal Heart Institute, Montréal, Canada;
  • Vilquin M; Maisonneuve-Rosemont Hospital, Research Center, Montreal, Canada;
  • Kuchroo V; Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and.
  • Michnick S; Department of Pharmacology and Therapeutics, McGill University, Montréal, Canada;
  • Rioux JD; Montreal Heart Institute, Montréal, Canada; Department of Medicine, Université de Montréal, Montréal, Canada.
  • Lesage S; Maisonneuve-Rosemont Hospital, Research Center, Montreal, Canada; Department of Microbiology and Immunology, Université de Montréal, Montréal, Canada;
  • Chemtob S; Departments of Pediatrics, Ophthalmology and Pharmacology, Centre Hospitalier Universitaire Sainte-Justine Research Centre, Montréal, Canada; sylvain.chemtob@umontreal.ca.
Am J Physiol Regul Integr Comp Physiol ; 307(10): R1216-30, 2014 Nov 15.
Article em En | MEDLINE | ID: mdl-25354400
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Receptores de Interleucina / Inflamação / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Idioma: En Revista: Am J Physiol Regul Integr Comp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Receptores de Interleucina / Inflamação / Anti-Inflamatórios Tipo de estudo: Prognostic_studies Idioma: En Revista: Am J Physiol Regul Integr Comp Physiol Assunto da revista: FISIOLOGIA Ano de publicação: 2014 Tipo de documento: Article