Antenatal corticosteroids and perinatal outcomes in infants born at 23-25 weeks of gestation.
J Matern Fetal Neonatal Med
; 28(17): 2084-9, 2015.
Article
em En
| MEDLINE
| ID: mdl-25367557
ABSTRACT
OBJECTIVES:
To evaluate the perinatal results of infants born between 23 and 25.6 weeks of gestation.METHODS:
Medical charts of all women giving birth prematurely (23-25.6 w) from January 2005 to December 2011 were retrospectively reviewed. Cases of malformed infants or deliveries elsewhere were excluded.RESULTS:
198 infants were included. Chorioamnionitis occurred in 86 (43.4%) of the whole group 26 (86.7%) in the 23-week; 35 (53.8%) in the 24-week and 25 (24.3%) in the 25-week groups. Foetal maturation with antenatal corticosteroids was complete in 119 cases (60.1%) 4 (13.3%) in the 23-week; 35 (53.8%) in the 24-week and 80 (77.7%) in the 25-week groups. Foetal death at birth occurred in 22 cases (11%) and 61 newborns (30.8%) died in the neonatal period. Of the 106 survivors with 2 years complete follow-up, 45 infants (42.4%) did not present sequelae; 16 infants (15.1%) had severe sequelae. A 66.6% (4) of infants born at 23 weeks of gestation did not present sequelae compared with a 32.3% (11) at 24 weeks and 45.4% (30) at 25 weeks.CONCLUSIONS:
The chorioamnionitis rate was higher when gestational age was lower. The foetal maturation rate was higher when gestational age was higher. A low severe sequelae rate was observed in the whole series, particularly in the 23-week group where the rate was lower than expected; however, these results could have been influenced by the small size of the 23-week group.Palavras-chave
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Resultado da Gravidez
/
Idade Gestacional
/
Corticosteroides
/
Maturidade dos Órgãos Fetais
/
Lactente Extremamente Prematuro
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Assunto da revista:
OBSTETRICIA
/
PERINATOLOGIA
Ano de publicação:
2015
Tipo de documento:
Article