TiO2 nanoparticle-induced neurotoxicity may be involved in dysfunction of glutamate metabolism and its receptor expression in mice.

Ze, Xiao; Su, Mingyu; Zhao, Xiaoyang; Jiang, Hao; Hong, Jie; Yu, Xiaohong; Liu, Dong; Xu, Bingqing; Sheng, Lei; Zhou, Qiuping; Zhou, Junling; Cui, Jingwen; Li, Kai; Wang, Ling; Ze, Yuguan; Hong, Fashui

Ze, Xiao; Su, Mingyu; Zhao, Xiaoyang; Jiang, Hao; Hong, Jie; Yu, Xiaohong; Liu, Dong; Xu, Bingqing; Sheng, Lei; Zhou, Qiuping; Zhou, Junling; Cui, Jingwen; Li, Kai; Wang, Ling; Ze, Yuguan; Hong, Fashui.

Afiliação

Ze X; Medical College of Soochow University, Suzhou, 215123, China.
Su M; Suzhou Environmental Monitor Center, Suzhou, 215004, China.
Zhao X; Medical College of Soochow University, Suzhou, 215123, China.
Jiang H; Medical College of Soochow University, Suzhou, 215123, China.
Hong J; Medical College of Soochow University, Suzhou, 215123, China.
Yu X; Medical College of Soochow University, Suzhou, 215123, China.
Liu D; Medical College of Soochow University, Suzhou, 215123, China.
Xu B; Medical College of Soochow University, Suzhou, 215123, China.
Sheng L; Medical College of Soochow University, Suzhou, 215123, China.
Zhou Q; Medical College of Soochow University, Suzhou, 215123, China.
Zhou J; Medical College of Soochow University, Suzhou, 215123, China.
Cui J; Medical College of Soochow University, Suzhou, 215123, China.
Li K; Medical College of Soochow University, Suzhou, 215123, China.
Wang L; Library of Soochow University, Suzhou, 215021, China.
Ze Y; Medical College of Soochow University, Suzhou, 215123, China.
Hong F; Medical College of Soochow University, Suzhou, 215123, China.

Environ Toxicol ; 31(6): 655-62, 2016 Jun.

Article em En | MEDLINE | ID: mdl-25411160

Assuntos

Encéfalo/efeitos dos fármacos; Nanopartículas Metálicas/toxicidade; Neurotoxinas/toxicidade; Titânio/toxicidade; Animais; Encéfalo/metabolismo; Relação Dose-Resposta a Droga; Feminino; Expressão Gênica/efeitos dos fármacos; Glutamato-Amônia Ligase/genética; Glutamato-Amônia Ligase/metabolismo; Ácido Glutâmico/genética; Ácido Glutâmico/metabolismo; Glutaminase/genética; Glutaminase/metabolismo; Glutamina/genética; Glutamina/metabolismo; Camundongos; Camundongos Endogâmicos ICR; Receptores de Glutamato Metabotrópico/genética; Receptores de Glutamato Metabotrópico/metabolismo

Palavras-chave

glutamate receptors; glutamate-glutamine cyclic pathway; hippocampus; mice; titanium dioxide nanoparticles

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Titânio / Encéfalo / Nanopartículas Metálicas / Neurotoxinas Limite: Animals Idioma: En Revista: Environ Toxicol Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China

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