[Multilocus sequence typing and its application on population genetic structure analysis of parasites].

ABSTRACT

Multilocus sequence typing (MLST) with high solution, sensitivity and specificity, is widely used to study the population genetic structure of pathogen by amplification and sequencing of the housekeeping genes. MLST also provides more evidence and plays an important role in parasite research. This paper reviews the principle and method of MLST, and its application on population genetic structure analysis of parasites.