HIF1A regulates xenophagic degradation of adherent and invasive Escherichia coli (AIEC).
Autophagy
; 10(12): 2333-45, 2014.
Article
em En
| MEDLINE
| ID: mdl-25484075
Palavras-chave
AIEC, adherent invasive E. coli; AMPK, AMP-activated protein kinase; ATG16L1, autophagy-related 16-like 1; ATG5, autophagy-related 5; BECN1, Beclin 1, autophagy-related; BNIP3L, BCL2/adenovirus E1B 19kDa interacting protein 3-like; CD, Crohn disease; CEACAM6, carcinoembryonic antigen-related cell adhesion molecule 6 (nonspecific cross reacting antigen); CRTC1/TORC1, CREB regulated transcription coactivator 1; Crohn disease; EEA1, early endosome antigen 1; GFP, green fluorescent protein; HBSS, Hank's balanced salt solution; HIF1A, hypoxia inducible factor 1, α subunit (basic helix-loop-helix transcription factor); IBD, inflammatory bowel disease; IRGM, immunity-related GTPase family, M; LAP; LAP, LC3-associated phagocytosis; MAP1LC3-II (LC3-II), microtubule-associated protein 1 light chain 3-II; MOI, multiplicity of infection; SQSTM1/p62 (SQSTM1), sequestosome 1; TEM, transmission electron microscopy; TLR5, toll-like receptor 5; ULK1, unc-51 like autophagy activating kinase 1; VAV2, vav 2 guanine nucleotide exchange factor; autophagy; bacteria; hypoxia inducible factor
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Autofagia
/
Células Epiteliais
/
Infecções por Escherichia coli
/
Subunidade alfa do Fator 1 Induzível por Hipóxia
Tipo de estudo:
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Autophagy
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
França