Pruritus: an underrecognized symptom of small-fiber neuropathies.
J Am Acad Dermatol
; 72(2): 328-32, 2015 Feb.
Article
em En
| MEDLINE
| ID: mdl-25484269
ABSTRACT
BACKGROUND:
Small-fiber neuropathies (SFN) are diseases of small nerve fibers that are characterized by autonomic and sensory symptoms.OBJECTIVE:
We sought to evaluate sensory symptoms, especially pruritus, in patients with SFN.METHODS:
A questionnaire was given to patients with SFN.RESULTS:
In all, 41 patients responded to the questionnaire (71.9% response rate). The most frequent sensory symptoms were burning (77.5%), pain (72.5%), heat sensations (70.2%), and numbness (67.5%). Pruritus was present in 68.3% of patients. It appeared most often in the evening, and was localized to the limbs in a distal-to-proximal gradient, although the back was the most frequent location (64%). Exacerbating factors were fatigue, xerosis, sweating, hot temperature, and stress. Cold water was an alleviating factor.LIMITATIONS:
Recall bias associated with filling out the questionnaire, relatively small sample size, and the uncontrolled, retrospective nature of the study were limitations.CONCLUSION:
Pruritus occurs frequently in patients with SFN and could be recognized as a possible presenting symptom, especially if there are other sensory or autonomic symptoms.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Prurido
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Eritromelalgia
Tipo de estudo:
Diagnostic_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Am Acad Dermatol
Ano de publicação:
2015
Tipo de documento:
Article