Sanguinarine inhibits Rac1b-rendered cell survival enhancement by promoting apoptosis and blocking proliferation.

Ying, Li; Li, Gang; Wei, Si-si; Wang, Hong; An, Pei; Wang, Xun; Guo, Kai; Luo, Xian-jin; Gao, Ji-min; Zhou, Qing; Li, Wei; Yu, Ying; Li, Yi-gang; Duan, Jun-li; Wang, Yue-peng

Ying, Li; Li, Gang; Wei, Si-si; Wang, Hong; An, Pei; Wang, Xun; Guo, Kai; Luo, Xian-jin; Gao, Ji-min; Zhou, Qing; Li, Wei; Yu, Ying; Li, Yi-gang; Duan, Jun-li; Wang, Yue-peng.

Afiliação

Ying L; 1] Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China [2] Gerontology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Li G; Pediatrics, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Wei SS; Department of Cardiology, Affiliated 10th People's Hospital, Shanghai Tongji University School of Medicine, Shanghai 200072, China.
Wang H; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
An P; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Wang X; Pediatrics, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Guo K; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Luo XJ; School of Chemistry and Chemical Engineering of SJTU, Shanghai 200240, China.
Gao JM; Key Laboratory of Laboratory Medicine of the Chinese Ministry of Education, Wenzhou Medical College, Wenzhou 325035, China.
Zhou Q; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Li W; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Yu Y; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Li YG; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Duan JL; Gerontology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.
Wang YP; Department of Cardiology, Affiliated Xinhua Hospital, Shanghai Jiaotong University (SJTU) School of Medicine, Shanghai 200092, China.

Acta Pharmacol Sin ; 36(2): 229-40, 2015 Feb.

Article em En | MEDLINE | ID: mdl-25544362

Assuntos

Apoptose/efeitos dos fármacos; Benzofenantridinas/farmacologia; Proliferação de Células/efeitos dos fármacos; Sobrevivência Celular/efeitos dos fármacos; Isoquinolinas/farmacologia; Proteínas rac1 de Ligação ao GTP/metabolismo; Linhagem Celular; Células HEK293; Humanos

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sobrevivência Celular / Apoptose / Proteínas rac1 de Ligação ao GTP / Proliferação de Células / Benzofenantridinas / Isoquinolinas Limite: Humans Idioma: En Revista: Acta Pharmacol Sin Assunto da revista: FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: China

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