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KUD773, a phenylthiazole derivative, displays anticancer activity in human hormone-refractory prostate cancers through inhibition of tubulin polymerization and anti-Aurora A activity.
Yu, Chia-Chun; Liu, Shih-Ping; Hsu, Jui-Ling; Hsu, John Ta; Kudryavtsev, Konstantin V; Guh, Jih-Hwa.
Afiliação
  • Yu CC; School of Pharmacy, National Taiwan University, Taipei, Taiwan. d98423007@ntu.edu.tw.
  • Liu SP; Department of Urology, National Taiwan University Hospital, Taipei, Taiwan. spliu@ntuh.gov.tw.
  • Hsu JL; School of Pharmacy, National Taiwan University, Taipei, Taiwan. juiling221@hotmail.com.
  • Hsu JT; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Zhunan, Taiwan. tsuanhsu@nhri.org.tw.
  • Kudryavtsev KV; Department of Medicinal Chemistry, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Moscow, Russian Federation. kudr@med.chem.msu.ru.
  • Guh JH; Institute of Physiologically Active Compounds, Russian Academy of Sciences, Moscow region, Russian Federation. kudr@med.chem.msu.ru.
J Biomed Sci ; 22: 2, 2015 Jan 07.
Article em En | MEDLINE | ID: mdl-25563361
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hiperplasia Prostática / Tiazóis / Tubulina (Proteína) / Apoptose / Moduladores de Tubulina / Antineoplásicos Limite: Humans / Male Idioma: En Revista: J Biomed Sci Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Taiwan
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hiperplasia Prostática / Tiazóis / Tubulina (Proteína) / Apoptose / Moduladores de Tubulina / Antineoplásicos Limite: Humans / Male Idioma: En Revista: J Biomed Sci Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Taiwan