Long-term survival in a case of pleomorphic carcinoma with a brain metastasis.
Case Rep Oncol
; 7(3): 799-803, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-25566055
ABSTRACT
Pleomorphic carcinoma (PC) is a rare malignant lung tumor with a poorer prognosis compared to other histological types of non-small cell lung cancer. However, several recent immunohistochemical studies revealed that a low MIB-1 index is a good prognostic marker in patients with PC. We report the case of a patient with PC and a single brain metastasis that achieved long-term recurrence-free survival following treatment with combined modality therapy. In this case, the MIB-1 index was reduced by gemcitabine-based chemotherapy, which may have led to long-term disease-free survival. The MIB-1 index may be a useful biomarker for the response to chemotherapy.
Texto completo:
1
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Case Rep Oncol
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Japão