Combination of proteasome and HDAC inhibitor enhances HPV16 E7-specific CD8+ T cell immune response and antitumor effects in a preclinical cervical cancer model.

Huang, Zhuomin; Peng, Shiwen; Knoff, Jayne; Lee, Sung Yong; Yang, Benjamin; Wu, Tzyy-Choou; Hung, Chien-Fu

Huang, Zhuomin; Peng, Shiwen; Knoff, Jayne; Lee, Sung Yong; Yang, Benjamin; Wu, Tzyy-Choou; Hung, Chien-Fu.

Afiliação

Huang Z; Department of Pathology, Johns Hopkins Medical Institutions, CRB II Room 307, 1550 Orleans Street, 21231, Baltimore, MD, USA. pyamyhuang@163.com.
Peng S; Department of Gynecology, Shenzhen Maternity and Child Healthcare Hospital, Southern Medical University, Shenzhen, China. pyamyhuang@163.com.
Knoff J; Department of Pathology, Johns Hopkins Medical Institutions, CRB II Room 307, 1550 Orleans Street, 21231, Baltimore, MD, USA. speng1@jhmi.edu.
Lee SY; Department of Pathology, Johns Hopkins Medical Institutions, CRB II Room 307, 1550 Orleans Street, 21231, Baltimore, MD, USA. jayne.knoff@gmail.com.
Yang B; Department of Pathology, Johns Hopkins Medical Institutions, CRB II Room 307, 1550 Orleans Street, 21231, Baltimore, MD, USA. pusarang@gmail.com.
Wu TC; Department of Internal Medicine, Korea University Medical Center, Seoul, South Korea. pusarang@gmail.com.
Hung CF; Department of Pathology, Johns Hopkins Medical Institutions, CRB II Room 307, 1550 Orleans Street, 21231, Baltimore, MD, USA. b.y.himself91@gmail.com.

J Biomed Sci ; 22: 7, 2015 Jan 16.

Article em En | MEDLINE | ID: mdl-25591912

Assuntos

Antineoplásicos/farmacologia; Bortezomib/farmacologia; Linfócitos T CD8-Positivos/efeitos dos fármacos; Ácidos Hidroxâmicos/farmacologia; Imunidade Inata/efeitos dos fármacos; Neoplasias do Colo do Útero/tratamento farmacológico; Animais; Linfócitos T CD8-Positivos/imunologia; Modelos Animais de Doenças; Feminino; Inibidores de Histona Desacetilases/farmacologia; Humanos; Camundongos; Camundongos Endogâmicos C57BL; Inibidores de Proteassoma/farmacologia; Neoplasias do Colo do Útero/imunologia; Vorinostat

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias do Colo do Útero / Linfócitos T CD8-Positivos / Bortezomib / Ácidos Hidroxâmicos / Imunidade Inata / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: J Biomed Sci Assunto da revista: MEDICINA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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