General and chemoselective bisphosphonylation of secondary and tertiary amides.

Wang, Ai-E; Chang, Zong; Sun, Wei-Ting; Huang, Pei-Qiang

Wang, Ai-E; Chang, Zong; Sun, Wei-Ting; Huang, Pei-Qiang.

Afiliação

Wang AE; Department of Chemistry, Fujian Provincial Key Laboratory of Chemical Biology, College of Chemistry and Chemical Engineering, and Collaborative Innovation Centre of Chemistry for Energy Materials, Xiamen University , Xiamen, Fujian 361005, P. R. China.

Org Lett ; 17(3): 732-5, 2015 Feb 06.

Article em En | MEDLINE | ID: mdl-25625596

ABSTRACT

ABSTRACT

With Tf2O as the activation reagent, a mild and general method has been developed for the bisphosphonylation of both secondary and tertiary amides. The protocol is highly efficient and chemoselective, and it tolerates a number of sensitive functional groups such as cyano, ester, and aldehyde groups.

Assuntos

Amidas/química; Furanos/química; Compostos Organofosforados/química; Sulfonamidas/química; Aldeídos/química; Catálise; Estrutura Molecular

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos Organofosforados / Sulfonamidas / Furanos / Amidas Idioma: En Revista: Org Lett Assunto da revista: BIOQUIMICA Ano de publicação: 2015 Tipo de documento: Article

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