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Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils.
Barthelmes, Julia; de Bazo, Anika Männer; Pewzner-Jung, Yael; Schmitz, Katja; Mayer, Christoph A; Foerch, Christian; Eberle, Max; Tafferner, Nadja; Ferreirós, Nerea; Henke, Marina; Geisslinger, Gerd; Futerman, Anthony H; Grösch, Sabine; Schiffmann, Susanne.
Afiliação
  • Barthelmes J; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • de Bazo AM; Department of Neurology, Goethe-University Frankfurt, Schleusenweg 2-16, 60528 Frankfurt/Main, Germany.
  • Pewzner-Jung Y; Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Schmitz K; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Mayer CA; Department of Neurology, Goethe-University Frankfurt, Schleusenweg 2-16, 60528 Frankfurt/Main, Germany.
  • Foerch C; Department of Neurology, Goethe-University Frankfurt, Schleusenweg 2-16, 60528 Frankfurt/Main, Germany.
  • Eberle M; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Tafferner N; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology (TMP), Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Ferreirós N; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Henke M; Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Project Group Translational Medicine and Pharmacology (TMP), Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Geisslinger G; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Futerman AH; Department of Biological Chemistry, Weizmann Institute of Science, Rehovot 76100, Israel.
  • Grösch S; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany.
  • Schiffmann S; Pharmazentrum frankfurt/ZAFES, Institut für Klinische Pharmakologie, Klinikum der Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt/Main, Germany. Electronic address: susanne.schiffmann@med.uni-frankfurt.de.
Brain Behav Immun ; 46: 280-92, 2015 May.
Article em En | MEDLINE | ID: mdl-25697397
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Movimento Celular / Encefalomielite Autoimune Experimental / Esfingosina N-Aciltransferase / Esclerose Múltipla / Neutrófilos Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Movimento Celular / Encefalomielite Autoimune Experimental / Esfingosina N-Aciltransferase / Esclerose Múltipla / Neutrófilos Tipo de estudo: Prognostic_studies Limite: Adult / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Brain Behav Immun Assunto da revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha