Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor.

Baudelet, Davy; Furman, Christophe; Ghinet, Alina; Dezitter, Xavier; Adriouch, Sahil; Capet, Frédéric; Rogez-Florent, Tiphaine; Gautret, Philippe; Rigo, Benoit; Millet, Régis; Vaccher, Claude; Lipka, Emmanuelle

Baudelet, Davy; Furman, Christophe; Ghinet, Alina; Dezitter, Xavier; Adriouch, Sahil; Capet, Frédéric; Rogez-Florent, Tiphaine; Gautret, Philippe; Rigo, Benoit; Millet, Régis; Vaccher, Claude; Lipka, Emmanuelle.

Afiliação

Baudelet D; Inserm U995, Université de Lille, Laboratoire de Chimie Analytique, UFR Pharmacie, F-59000 Lille, France; Inserm U995, Université de Lille, Hautes Etudes Ingénieur, F-59000 Lille, France.
Furman C; Université de Lille, UDSL, Plateforme de binding, ICPAL, F-59000 Lille, France.
Ghinet A; Inserm U995, Université de Lille, Hautes Etudes Ingénieur, F-59000 Lille, France.
Dezitter X; Université de Lille, UDSL, Plateforme de binding, ICPAL, F-59000 Lille, France.
Adriouch S; Inserm 905, Université de Rouen, Département de Médecine, F-76983 Rouen, France.
Capet F; Université de Lille, USTL, UMR 8181, Unité de Catalyse et de Chimie du Solide, F-59000 Lille, France.
Rogez-Florent T; Université de Lille, EA GRITA, Laboratoire de Chimie Analytique, UFR Pharmacie, F-59000 Lille, France.
Gautret P; Inserm U995, Université de Lille, Hautes Etudes Ingénieur, F-59000 Lille, France.
Rigo B; Inserm U995, Université de Lille, Laboratoire de Chimie Analytique, UFR Pharmacie, F-59000 Lille, France.
Millet R; Inserm U995, Université de Lille, Laboratoire de Chimie Analytique, UFR Pharmacie, F-59000 Lille, France.
Vaccher C; Université de Lille, EA GRITA, Laboratoire de Chimie Analytique, UFR Pharmacie, F-59000 Lille, France.
Lipka E; Inserm U995, Université de Lille, Laboratoire de Chimie Analytique, UFR Pharmacie, F-59000 Lille, France. Electronic address: emmanuelle.lipka@univ-lille2.fr.

J Chromatogr B Analyt Technol Biomed Life Sci ; 986-987: 35-43, 2015 Apr 01.

Article em En | MEDLINE | ID: mdl-25703951

Assuntos

Amilose/análogos & derivados; Celulose/análogos & derivados; Cromatografia Líquida de Alta Pressão/métodos; Fenilcarbamatos/química; Antagonistas do Receptor Purinérgico P2X/química; Antagonistas do Receptor Purinérgico P2X/isolamento & purificação; Amilose/química; Celulose/química; Modelos Lineares; Antagonistas do Receptor Purinérgico P2X/análise; Reprodutibilidade dos Testes; Sensibilidade e Especificidade; Estereoisomerismo

Palavras-chave

Amylose tris (3,5-dimethylphenylcarbamate); Capillary electrophoresis; Dual cyclodextrins system; High performance liquid chromatography; N-[1-(2,4-Dichlorobenzyl)-5-oxopyrrolidin-2-yl]-2-(2,4-dichlorophenyl) acetamide; Supercritical fluid chromatography

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Celulose / Cromatografia Líquida de Alta Pressão / Fenilcarbamatos / Antagonistas do Receptor Purinérgico P2X / Amilose Tipo de estudo: Diagnostic_studies / Prognostic_studies Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google