p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency.

Belle, Jad I; Langlais, David; Petrov, Jessica C; Pardo, Mercedes; Jones, Russell G; Gros, Philippe; Nijnik, Anastasia

Belle, Jad I; Langlais, David; Petrov, Jessica C; Pardo, Mercedes; Jones, Russell G; Gros, Philippe; Nijnik, Anastasia.

Afiliação

Belle JI; Department of Physiology, Complex Traits Group, and.
Langlais D; Complex Traits Group, and Department of Biochemistry, McGill University, Montreal, QC, Canada;
Petrov JC; Department of Physiology, Complex Traits Group, and.
Pardo M; Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, United Kingdom; and.
Jones RG; Department of Physiology, The Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada.
Gros P; Complex Traits Group, and Department of Biochemistry, McGill University, Montreal, QC, Canada; The Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, QC, Canada.
Nijnik A; Department of Physiology, Complex Traits Group, and.

Blood ; 125(15): 2344-8, 2015 Apr 09.

Article em En | MEDLINE | ID: mdl-25710881

Assuntos

Endopeptidases/genética; Células-Tronco Hematopoéticas/patologia; Linfopenia/genética; Linfopoese; Proteína Supressora de Tumor p53/metabolismo; Animais; Deleção de Genes; Células-Tronco Hematopoéticas/metabolismo; Linfopenia/metabolismo; Linfopenia/patologia; Camundongos; Camundongos Knockout; Transativadores; Proteína Supressora de Tumor p53/genética; Proteases Específicas de Ubiquitina

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Endopeptidases / Células-Tronco Hematopoéticas / Proteína Supressora de Tumor p53 / Linfopoese / Linfopenia Limite: Animals Idioma: En Revista: Blood Ano de publicação: 2015 Tipo de documento: Article

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