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Compartmentalized accumulation of cAMP near complexes of multidrug resistance protein 4 (MRP4) and cystic fibrosis transmembrane conductance regulator (CFTR) contributes to drug-induced diarrhea.
Moon, Changsuk; Zhang, Weiqiang; Ren, Aixia; Arora, Kavisha; Sinha, Chandrima; Yarlagadda, Sunitha; Woodrooffe, Koryse; Schuetz, John D; Valasani, Koteswara Rao; de Jonge, Hugo R; Shanmukhappa, Shiva Kumar; Shata, Mohamed Tarek M; Buddington, Randal K; Parthasarathi, Kaushik; Naren, Anjaparavanda P.
Afiliação
  • Moon C; From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, the Departments of Physiology and.
  • Zhang W; the Departments of Physiology and Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee 38163.
  • Ren A; the Departments of Physiology and the Departments of Hematology and.
  • Arora K; From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, the Departments of Physiology and.
  • Sinha C; the Departments of Physiology and.
  • Yarlagadda S; From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, the Departments of Physiology and.
  • Woodrooffe K; From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
  • Schuetz JD; Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
  • Valasani KR; the Department of Pharmacology and Toxicology and Higuchi Bioscience Center, School of Pharmacy, University of Kansas, Lawrence, Kansas 66047.
  • de Jonge HR; the Department of Gastroenterology and Hepatology, Erasmus University Medical Center, 3000CA Rotterdam, The Netherlands.
  • Shanmukhappa SK; From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
  • Shata MT; the Division of Digestive Diseases, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, and.
  • Buddington RK; the Department of Health and Sport Sciences, University of Memphis, Memphis, Tennessee 38152.
  • Parthasarathi K; the Departments of Physiology and.
  • Naren AP; From the Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229, the Departments of Physiology and anaren@cchmc.org.
J Biol Chem ; 290(18): 11246-57, 2015 May 01.
Article em En | MEDLINE | ID: mdl-25762723

Texto completo: 1 Base de dados: MEDLINE Assunto principal: AMP Cíclico / Regulador de Condutância Transmembrana em Fibrose Cística / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Diarreia Limite: Animals / Humans País/Região como assunto: America do norte Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: AMP Cíclico / Regulador de Condutância Transmembrana em Fibrose Cística / Proteínas Associadas à Resistência a Múltiplos Medicamentos / Diarreia Limite: Animals / Humans País/Região como assunto: America do norte Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article