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Co-activation of PIK3CA and Yap promotes development of hepatocellular and cholangiocellular tumors in mouse and human liver.
Li, Xiaolei; Tao, Junyan; Cigliano, Antonio; Sini, Marcella; Calderaro, Julien; Azoulay, Daniel; Wang, Chunmei; Liu, Yan; Jiang, Lijie; Evert, Katja; Demartis, Maria I; Ribback, Silvia; Utpatel, Kirsten; Dombrowski, Frank; Evert, Matthias; Calvisi, Diego F; Chen, Xin.
Afiliação
  • Li X; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, P.R. China.
  • Tao J; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, U.S.A.
  • Cigliano A; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, U.S.A.
  • Sini M; School of Pharmacy, Hubei University of Chinese Medicine, Wuhan, Hubei, P.R. China.
  • Calderaro J; Institute of Pathology, University Medicine of Greifswald, Greifswald, Germany.
  • Azoulay D; Institute of Pathology, University Medicine of Greifswald, Greifswald, Germany.
  • Wang C; Department of Pathology, Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Universitaire Henri Mondor, Créteil, France.
  • Liu Y; Inserm, U1162, Génomique Fonctionnelle des Tumeurs Solides, Institut Universitaire d'Hematologie, Paris, France.
  • Jiang L; Department of Digestive and Hepatobiliairy Surgery, Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Universitaire Henri Mondor, Créteil, France.
  • Evert K; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, U.S.A.
  • Demartis MI; Department of Hepatobiliary Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi, P.R. China.
  • Ribback S; Department of Bioengineering and Therapeutic Sciences and Liver Center, University of California, San Francisco, CA, U.S.A.
  • Utpatel K; Institute of Pathology, University Medicine of Greifswald, Greifswald, Germany.
  • Dombrowski F; Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy.
  • Evert M; Institute of Pathology, University Medicine of Greifswald, Greifswald, Germany.
  • Calvisi DF; Institute of Pathology, University Medicine of Greifswald, Greifswald, Germany.
  • Chen X; Institute of Pathology, University Medicine of Greifswald, Greifswald, Germany.
Oncotarget ; 6(12): 10102-15, 2015 Apr 30.
Article em En | MEDLINE | ID: mdl-25826091
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Colangiocarcinoma / Carcinoma Hepatocelular / Fosfatidilinositol 3-Quinases / Proteínas Adaptadoras de Transdução de Sinal / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfoproteínas / Colangiocarcinoma / Carcinoma Hepatocelular / Fosfatidilinositol 3-Quinases / Proteínas Adaptadoras de Transdução de Sinal / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Oncotarget Ano de publicação: 2015 Tipo de documento: Article