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Nicorandil prevents sirolimus-induced production of reactive oxygen species, endothelial dysfunction, and thrombus formation.
Aizawa, Ken; Takahari, Youko; Higashijima, Naoko; Serizawa, Kenichi; Yogo, Kenji; Ishizuka, Nobuhiko; Endo, Koichi; Fukuyama, Naoto; Hirano, Katsuya; Ishida, Hideyuki.
Afiliação
  • Aizawa K; Product Research Department, Chugai Pharmaceutical Co., Ltd., Shizuoka 412-8513, Japan.
  • Takahari Y; Teaching and Research Support Center, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
  • Higashijima N; Department of Physiology, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
  • Serizawa K; Product Research Department, Chugai Pharmaceutical Co., Ltd., Shizuoka 412-8513, Japan.
  • Yogo K; Product Research Department, Chugai Pharmaceutical Co., Ltd., Shizuoka 412-8513, Japan.
  • Ishizuka N; Product Research Department, Chugai Pharmaceutical Co., Ltd., Shizuoka 412-8513, Japan.
  • Endo K; Product Research Department, Chugai Pharmaceutical Co., Ltd., Shizuoka 412-8513, Japan.
  • Fukuyama N; Department of Physiology, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
  • Hirano K; Department of Cardiovascular Physiology, Faculty of Medicine, Kagawa University, Kagawa 761-0793, Japan. Electronic address: khirano@med.kagawa-u.ac.jp.
  • Ishida H; Department of Physiology, Tokai University School of Medicine, Kanagawa 259-1193, Japan.
J Pharmacol Sci ; 127(3): 284-91, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25837924
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Espécies Reativas de Oxigênio / Sirolimo / Nicorandil / Células Endoteliais / Antiarrítmicos Limite: Animals / Humans / Male Idioma: En Revista: J Pharmacol Sci Assunto da revista: FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Trombose / Espécies Reativas de Oxigênio / Sirolimo / Nicorandil / Células Endoteliais / Antiarrítmicos Limite: Animals / Humans / Male Idioma: En Revista: J Pharmacol Sci Assunto da revista: FARMACOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão