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LP99: Discovery and Synthesis of the First Selective BRD7/9 Bromodomain Inhibitor.
Clark, Peter G K; Vieira, Lucas C C; Tallant, Cynthia; Fedorov, Oleg; Singleton, Dean C; Rogers, Catherine M; Monteiro, Octovia P; Bennett, James M; Baronio, Roberta; Müller, Susanne; Daniels, Danette L; Méndez, Jacqui; Knapp, Stefan; Brennan, Paul E; Dixon, Darren J.
Afiliação
  • Clark PG; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).
  • Vieira LC; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK).
  • Tallant C; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Fedorov O; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Singleton DC; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Rogers CM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Monteiro OP; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Bennett JM; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Baronio R; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Müller S; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Daniels DL; Promega Corporation, 2800 Woods Hollow Road, Madison, W153611 (USA).
  • Méndez J; Promega Corporation, 2800 Woods Hollow Road, Madison, W153611 (USA).
  • Knapp S; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK).
  • Brennan PE; Structural Genomics Consortium & Target Discovery Institute, University of Oxford, NDM Research Building, Roosevelt Drive, Oxford, OX3 7DQ and OX3 7FZ (UK). paul.brennan@sgc.ox.ac.uk.
  • Dixon DJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK). darren.dixon@chem.ox.ac.uk.
Angew Chem Int Ed Engl ; 54(21): 6217-21, 2015 May 18.
Article em En | MEDLINE | ID: mdl-25864491
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Cromossômicas não Histona / Descoberta de Drogas / Lactamas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas Cromossômicas não Histona / Descoberta de Drogas / Lactamas Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Angew Chem Int Ed Engl Ano de publicação: 2015 Tipo de documento: Article