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Matrix stiffness drives epithelial-mesenchymal transition and tumour metastasis through a TWIST1-G3BP2 mechanotransduction pathway.
Wei, Spencer C; Fattet, Laurent; Tsai, Jeff H; Guo, Yurong; Pai, Vincent H; Majeski, Hannah E; Chen, Albert C; Sah, Robert L; Taylor, Susan S; Engler, Adam J; Yang, Jing.
Afiliação
  • Wei SC; 1] Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA [2] The Biomedical Sciences Graduate Program, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Fattet L; Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Tsai JH; Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Guo Y; Howard Hughes Medical Institute, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Pai VH; 1] Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA [2] The Biomedical Sciences Graduate Program, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Majeski HE; 1] Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA [2] The Biomedical Sciences Graduate Program, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Chen AC; Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Sah RL; Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Taylor SS; 1] Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA [2] Howard Hughes Medical Institute, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA [3] Department of Chemistry and Biochemistry, Un
  • Engler AJ; Department of Bioengineering, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
  • Yang J; 1] Department of Pharmacology, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA [2] Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive La Jolla, California 92093-0819, USA.
Nat Cell Biol ; 17(5): 678-88, 2015 May.
Article em En | MEDLINE | ID: mdl-25893917
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas Nucleares / Proteínas de Transporte / Carcinoma Intraductal não Infiltrante / Junções Célula-Matriz / Mecanotransdução Celular / Proteína 1 Relacionada a Twist / Matriz Extracelular / Transição Epitelial-Mesenquimal Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Proteínas Nucleares / Proteínas de Transporte / Carcinoma Intraductal não Infiltrante / Junções Célula-Matriz / Mecanotransdução Celular / Proteína 1 Relacionada a Twist / Matriz Extracelular / Transição Epitelial-Mesenquimal Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Nat Cell Biol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos