New dual-stage pH control fed-batch cultivation strategy for the improvement of lipids and carotenoids production by the red yeast Rhodosporidium toruloides NCYC 921.
Bioresour Technol
; 189: 309-318, 2015.
Article
em En
| MEDLINE
| ID: mdl-25898094
ABSTRACT
The optimal medium pH to produce biomass and fatty acids by the red yeast Rhodosporidium toruloides NCYC 921 is 4.0, and to produce carotenoids is 5.0. Based on this difference, a dual-stage pH control fed-batch cultivation strategy for the enhancement of lipids and carotenoids production by this yeast was studied. The results showed that when the yeast growth phase was conducted at pH 4.0, and the products accumulation phase was conducted at pH 5.0, biomass, total fatty acid and total carotenoid productivities were significantly improved comparing with the yeast fed batch cultivations carried out at fixed medium pH (4 or 5). Under dual-stage pH control conditions, the biomass, carotenoids and lipids productivities attained 2.35 g/Lh, 0.29 g/Lh and 0.40 g/Lh, respectively. It was also observed that the oxygen played a major role in the yeast carotenoid production.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Basidiomycota
/
Carotenoides
/
Técnicas de Cultura Celular por Lotes
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Lipídeos
Idioma:
En
Revista:
Bioresour Technol
Assunto da revista:
ENGENHARIA BIOMEDICA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Portugal