Increase in choline acetyltransferase activity in septum of rats after transient forebrain ischemia: a possible role of factors released in the hippocampus.

Hisanaga, K; Kogure, K; Tsukui, H; Takei, N; Nishio, C; Hatanaka, H

Hisanaga, K; Kogure, K; Tsukui, H; Takei, N; Nishio, C; Hatanaka, H.

Afiliação

Hisanaga K; Department of Neuroscience, Mitsubishi Kasai Institute of Life Sciences, Tokyo, Japan.

Neurosci Lett ; 105(3): 321-5, 1989 Nov 06.

Article em En | MEDLINE | ID: mdl-2594217

ABSTRACT

ABSTRACT

Choline acetyltransferase (ChAT) activity increased in rat septum 2 weeks after a transient forebrain ischemia. Extracts were prepared from hippocampus in which CA1 pyramidal neurons had been selectively destroyed by the ischemic insult. ChAT activity in septal neuronal cultures treated with these extracts for 6 days was significantly higher than that in control cultures.

Assuntos

Isquemia Encefálica/enzimologia; Colina O-Acetiltransferase/metabolismo; Hipocampo/metabolismo; Septo Pelúcido/enzimologia; Animais; Masculino; Neurônios/metabolismo; Ratos; Ratos Endogâmicos

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Base de dados: MEDLINE Assunto principal: Septo Pelúcido / Isquemia Encefálica / Colina O-Acetiltransferase / Hipocampo Limite: Animals Idioma: En Revista: Neurosci Lett Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Japão

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