Feedback circuitry between miR-218 repression and RTK activation in glioblastoma.

Mathew, Lijoy K; Huangyang, Peiwei; Mucaj, Vera; Lee, Samuel S; Skuli, Nicolas; Eisinger-Mathason, T S Karin; Biju, Kevin; Li, Bo; Venneti, Sriram; Lal, Priti; Lathia, Justin D; Rich, Jeremy N; Keith, Brian; Simon, M Celeste

Mathew, Lijoy K; Huangyang, Peiwei; Mucaj, Vera; Lee, Samuel S; Skuli, Nicolas; Eisinger-Mathason, T S Karin; Biju, Kevin; Li, Bo; Venneti, Sriram; Lal, Priti; Lathia, Justin D; Rich, Jeremy N; Keith, Brian; Simon, M Celeste.

Afiliação

Mathew LK; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Huangyang P; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mucaj V; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lee SS; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Skuli N; INSERM U1037, Institut Claudius Regaud, 20-24 Rue du Pont Saint-Pierre, 31059 Toulouse, France.
Eisinger-Mathason TS; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Biju K; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Li B; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Venneti S; Department of Pathology and Laboratory Medicine, Institut Claudius Regaud, 31059 Toulouse, France.
Lal P; Department of Pathology and Laboratory Medicine, Institut Claudius Regaud, 31059 Toulouse, France.
Lathia JD; Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Rich JN; Department of Stem Cell and Regenerative Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Keith B; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Cancer Biology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Simon MC; Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Howard Hughes Medical Institute, University of Pennsylvania, Philadelphia, PA 19104, USA. Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA 19104, USA. celeste

Sci Signal ; 8(375): ra42, 2015 May 05.

Article em En | MEDLINE | ID: mdl-25943352

Assuntos

Receptores ErbB/metabolismo; Regulação Neoplásica da Expressão Gênica; Glioblastoma/metabolismo; MicroRNAs/metabolismo; RNA Neoplásico/metabolismo; Receptores do Fator de Crescimento Derivado de Plaquetas/metabolismo; Transdução de Sinais; Linhagem Celular Tumoral; Receptores ErbB/genética; Glioblastoma/genética; Glioblastoma/patologia; Humanos; MicroRNAs/genética; RNA Neoplásico/genética; Receptores do Fator de Crescimento Derivado de Plaquetas/genética; Proteínas Repressoras/genética; Proteínas Repressoras/metabolismo; Proteínas Supressoras de Tumor/genética; Proteínas Supressoras de Tumor/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Neoplásico / Transdução de Sinais / Regulação Neoplásica da Expressão Gênica / Receptores do Fator de Crescimento Derivado de Plaquetas / Glioblastoma / MicroRNAs / Receptores ErbB Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Sci Signal Assunto da revista: CIENCIA / FISIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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