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Expression Analysis of Visual Arrestin gene during Ocular Development of Olive Flounder (Paralichthys olivaceus).
Yang, Hyun; Lee, Young Mee; Noh, Jae Koo; Kim, Hyun Chul; Park, Choul-Ji; Park, Jong-Won; Hwang, In Joon; Kim, Sung Yeon; Lee, Jeong-Ho.
Afiliação
  • Yang H; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Lee YM; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Noh JK; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Kim HC; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Park CJ; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Park JW; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Hwang IJ; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Kim SY; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
  • Lee JH; Genetics and Breeding Research Center, NFRDI, Geoje 656-842, Republic of Korea.
Dev Reprod ; 17(3): 231-40, 2013 Sep.
Article em En | MEDLINE | ID: mdl-25949138
ABSTRACT
Olive flounder (Paralichthys olivaceus) is one of the commercial important flatfish species in Korea. The ocular signal transduction pathway is important in newly hatched flounders because it is closely involved in the initial feeding phase thus essential for survival during the juvenile period. However, the study of gene expression during ocular development is incomplete in olive flounder. Therefore we examined the expression analysis of specifically induced genes during the development of the visual system in newly hatched flounders. We searched ocular development-involved gene in the database of expressed sequence tags (ESTs) from olive flounder eye and this gene similar to arrestin with a partial sequence homology. Microscopic observation of retinal formation corresponded with the time of expression of the arrestin gene in the developmental stage. These results suggest that arrestin plays a vital role in the visual signal transduction pathway of the retina during ocular development. The expression of arrestin was strong in the ocular system during the entirety of the development stages. Our findings regarding arrestin have important implications with respect to its biological role and evolution of G-protein coupled receptor (GPCR) signaling in olive flounder. Further studies are required on the GPCR-mediated signaling pathway and to decipher the functional role of arrestin.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Dev Reprod Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Revista: Dev Reprod Ano de publicação: 2013 Tipo de documento: Article