Intracellular nicotinamide adenine dinucleotide promotes TNF-induced necroptosis in a sirtuin-dependent manner.

Preyat, N; Rossi, M; Kers, J; Chen, L; Bertin, J; Gough, P J; Le Moine, A; Rongvaux, A; Van Gool, F; Leo, O

Preyat, N; Rossi, M; Kers, J; Chen, L; Bertin, J; Gough, P J; Le Moine, A; Rongvaux, A; Van Gool, F; Leo, O.

Afiliação

Preyat N; Laboratory of Immunobiology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, Gosselies, Belgium.
Rossi M; Institute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Kers J; Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Chen L; Center for Drug Design, Academic Health Center, University of Minnesota, Minneapolis, MN 55455, USA.
Bertin J; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
Gough PJ; Pattern Recognition Receptor Discovery Performance Unit, Immuno-Inflammation Therapeutic Area, GlaxoSmithKline, Collegeville, PA 19426, USA.
Le Moine A; Institute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.
Rongvaux A; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Van Gool F; Diabetes Center, University of California San Francisco, San Francisco, CA, USA.
Leo O; Laboratory of Immunobiology, Institute for Molecular Biology and Medicine, Université Libre de Bruxelles, Gosselies, Belgium.

Cell Death Differ ; 23(1): 29-40, 2016 Jan.

Article em En | MEDLINE | ID: mdl-26001219

Assuntos

NAD/metabolismo; Necrose/genética; Sirtuína 2/genética; Sirtuínas/genética; Apoptose/genética; Linhagem Celular; Citoplasma/metabolismo; Proteína Ligante Fas/genética; Proteína Ligante Fas/metabolismo; Humanos; Ligantes; NAD/genética; Necrose/metabolismo; Proteína Serina-Treonina Quinases de Interação com Receptores/genética; Proteína Serina-Treonina Quinases de Interação com Receptores/metabolismo; Sirtuína 2/metabolismo; Sirtuínas/metabolismo; Fator de Necrose Tumoral alfa/genética; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sirtuínas / Sirtuína 2 / NAD / Necrose Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cell Death Differ Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Bélgica

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