Frequency of Spontaneous Resistance to Peptide Deformylase Inhibitor GSK1322322 in Haemophilus influenzae, Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae.

Min, Sharon; Ingraham, Karen; Huang, Jianzhong; McCloskey, Lynn; Rilling, Sarah; Windau, Anne; Pizzollo, Jason; Butler, Deborah; Aubart, Kelly; Miller, Linda A; Zalacain, Magdalena; Holmes, David J; O'Dwyer, Karen

Min, Sharon; Ingraham, Karen; Huang, Jianzhong; McCloskey, Lynn; Rilling, Sarah; Windau, Anne; Pizzollo, Jason; Butler, Deborah; Aubart, Kelly; Miller, Linda A; Zalacain, Magdalena; Holmes, David J; O'Dwyer, Karen.

Afiliação

Min S; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA sharon.b.min@gsk.com.
Ingraham K; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Huang J; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
McCloskey L; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Rilling S; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Windau A; Laboratory Specialists, Inc., Westlake, Ohio, USA.
Pizzollo J; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Butler D; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Aubart K; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Miller LA; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Zalacain M; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
Holmes DJ; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.
O'Dwyer K; Antibacterial Discovery Performance Unit, Infectious Disease Therapeutic Area, GlaxoSmithKline, Collegeville, Pennsylvania, USA.

Antimicrob Agents Chemother ; 59(8): 4644-52, 2015 Aug.

Article em En | MEDLINE | ID: mdl-26014938

Assuntos

Amidoidrolases/antagonistas & inibidores; Antibacterianos/farmacologia; Compostos Bicíclicos Heterocíclicos com Pontes/farmacologia; Haemophilus influenzae/efeitos dos fármacos; Ácidos Hidroxâmicos/farmacologia; Staphylococcus aureus/efeitos dos fármacos; Streptococcus pneumoniae/efeitos dos fármacos; Streptococcus pyogenes/efeitos dos fármacos; Infecções por Haemophilus/tratamento farmacológico; Humanos; Testes de Sensibilidade Microbiana/métodos; Infecções Pneumocócicas/tratamento farmacológico; Infecções Estafilocócicas/tratamento farmacológico

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Staphylococcus aureus / Streptococcus pneumoniae / Streptococcus pyogenes / Haemophilus influenzae / Compostos Bicíclicos Heterocíclicos com Pontes / Amidoidrolases / Ácidos Hidroxâmicos / Antibacterianos Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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