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Safety and Pharmacokinetics/Pharmacodynamics of the First-in-Class Dual Action HER3/EGFR Antibody MEHD7945A in Locally Advanced or Metastatic Epithelial Tumors.
Juric, Dejan; Dienstmann, Rodrigo; Cervantes, Andres; Hidalgo, Manuel; Messersmith, Wells; Blumenschein, George R; Tabernero, Josep; Roda, Desamparados; Calles, Antonio; Jimeno, Antonio; Wang, Xiaodong; Bohórquez, Sandra Sanabria; Leddy, Cecilia; Littman, Catherine; Kapp, Amy V; Shames, David S; Penuel, Elicia; Amler, Lukas C; Pirzkall, Andrea; Baselga, José.
Afiliação
  • Juric D; Massachusetts General Hospital Cancer Center, Boston, Massachusetts.
  • Dienstmann R; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Cervantes A; Biomedical Research Institute INCLIVA, University of Valencia, Valencia, Spain.
  • Hidalgo M; Spanish National Cancer Research Center, Madrid, Spain.
  • Messersmith W; University of Colorado Cancer Center, Denver, Colorado.
  • Blumenschein GR; University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Tabernero J; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
  • Roda D; Biomedical Research Institute INCLIVA, University of Valencia, Valencia, Spain.
  • Calles A; Spanish National Cancer Research Center, Madrid, Spain.
  • Jimeno A; University of Colorado Cancer Center, Denver, Colorado.
  • Wang X; Genentech, Inc., South San Francisco, California.
  • Bohórquez SS; Genentech, Inc., South San Francisco, California.
  • Leddy C; Genentech, Inc., South San Francisco, California.
  • Littman C; Genentech, Inc., South San Francisco, California.
  • Kapp AV; Genentech, Inc., South San Francisco, California.
  • Shames DS; Genentech, Inc., South San Francisco, California.
  • Penuel E; Genentech, Inc., South San Francisco, California.
  • Amler LC; Genentech, Inc., South San Francisco, California.
  • Pirzkall A; Genentech, Inc., South San Francisco, California.
  • Baselga J; Massachusetts General Hospital Cancer Center, Boston, Massachusetts. baselgaj@mskcc.org.
Clin Cancer Res ; 21(11): 2462-70, 2015 Jun 01.
Article em En | MEDLINE | ID: mdl-26034219
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Carcinoma de Células Escamosas / Carcinoma Pulmonar de Células não Pequenas / Receptor ErbB-3 / Receptores ErbB / Neoplasias de Cabeça e Pescoço Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Carcinoma de Células Escamosas / Carcinoma Pulmonar de Células não Pequenas / Receptor ErbB-3 / Receptores ErbB / Neoplasias de Cabeça e Pescoço Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2015 Tipo de documento: Article