High throughput cross-interaction measures for human IgG1 antibodies correlate with clearance rates in mice.
MAbs
; 7(4): 770-7, 2015.
Article
em En
| MEDLINE
| ID: mdl-26047159
Palavras-chave
AC-SINS, affinity capture self-interaction nanoparticle spectroscopy; CIC, cross-interaction chromatography; CSI-BLI, clone self-interaction-biolayer interferometry; PK; PSR, poly specificity reagent; SEC, size exclusion chromatography; SMP, soluble membrane proteins; clearance; cross-interaction; developability; high throughput screening; mAb, monoclonal antibody; monoclonal antibody; non-specificity; self-interaction; stickiness
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
/
Anticorpos Monoclonais
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
MAbs
Assunto da revista:
ALERGIA E IMUNOLOGIA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Estados Unidos